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Geodesic Cells

Dynamic AFM image of a live rat mesenchymal stem cell showing both linear and geodesic arrangements of the F-actin cytoskeleton.  The high energy dissipation indicated at the geodesic vertices confirms the prediction of Lazarides (J. Cell. Biol. 68, 202-219 (1976)) that the vertices should have higher flexibility based on the absence of tropomyosin and myosin at these junctions. 90µm scan.  For more information, see HFSP Journal, 1, 181-191 (2007). Image courtesy of Suzi Jarvis and colleagues, Conway Institute  for Biomolecular and Biomedical Research, University College Dublin

 


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