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Ghost Parental Osteocarcinoma Cells in Buffer
Ghost parental Osteocarcinoma cells were imaged in contact mode
in buffer using an
Olympus TR400 cantilever. The above
is a composite of an optical micrograph (gray) and a 3D rendering
of the AFM
deflection data from the cell underneath the cantilever tip (blue).
While the overall shape of the cell is the same
in both images, the AFM data
shows stress fibers in the cytoskeleton not seen in the optical micrograph.
Sample courtesy of D. Wirtz, Dept. Chemical and Biomolecular Engineering, Johns Hopkins University.